International Journal of Ophthalmology Sciences

International Journal of Ophthalmology Sciences


International Journal of Ophthalmology Sciences
International Journal of Ophthalmology Sciences
2020, Vol. 2, Issue 1
Association of glycosylated hemoglobin (HbA1C) level with diabetic retinopathy in type 2 diabetes patients at tertiary care hospital

Kalpna Jain, Suman Devi, Poonam Bhargava, Lakshita Maherda, Dinesh Kumar Yadav

Introduction: Diabetic retinopathy (DR) is a chronic progressive, potentially sight-threatening disease of the retinal microvasculature associated with the prolonged hyperglycemia and associated with other condition. HbA1C is an important predictor for early identification of diabetic retinopathy cases. Materials and Method: It is a hospital based prospective observational study to assess association of HbA1Clevels with Diabetic retinopathy in type 2 Diabetes. The study included 160 DR cases. All calculations were performed using SPSS® version 15 (Statistical Packages for the Social Sciences, Chicago). Results: Maximum cases 88(55%) were developed diabetic retinopathy after 10 year. Mean duration of diabetes in (years) study population was 12.28± 6.05 years. 77.27% of mild NPDR cases were in range of 6.5-8.5% range of HbA1C. 60.72% moderate NPDR were in range 8.6-10.5% of HbA1C. 80% severe NPDR were in range 10.6-12.5% of HbA1C, whereas 80% PDR cases were in 12.6-14.5% range of HbA1C. Hb1Ac range was statistically significantly associated with progression of diabetic retinopathy (P=.001). Conclusion: Maximum number of patients 84 (52.5 % )were developed diabetic retinopathy after 60 years of life and maximum patients 88(55%) were developed diabetic retinopathy after 10 years duration of disease. Glycosylated hemoglobin value (HbA1C %) showed increasing trend according to severity of diabetic retinopathy cases hence prevalence and severity of diabetic retinopathy increased with increasing level of HbA1C
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